Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim

BACKGROUND: A common approach to cancer therapy in clinical practice is the combination of several drugs to boost the anticancer activity of available drugs while suppressing their unwanted side effects. In this regard, we examined the efficacy of combination treatment with the widely-used genotoxic...

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Bibliographic Details
Main Authors: Park, Hye-Kyung, Lee, Ji-Eun, Lim, Jaehwa, Jo, Da-Eun, Park, Soo-Ah, Suh, Pann-Ghill, Kang, Byoung Heon
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072609/
https://ncbi.nlm.nih.gov/pubmed/24927938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-431
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