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Kinetochore-microtubule stability governs the metaphase requirement for Eg5

The mitotic spindle is a bipolar, microtubule (MT)-based cellular machine that segregates the duplicated genome into two daughter cells. The kinesin-5 Eg5 establishes the bipolar geometry of the mitotic spindle, but previous work in mammalian cells suggested that this motor is unimportant for the ma...

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Hlavní autoři: Gayek, A. Sophia, Ohi, Ryoma
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072578/
https://ncbi.nlm.nih.gov/pubmed/24807901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0785
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