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A cell-intrinsic inhibitor of HIV-1 reverse transcription in CD4(+) T cells from elite controllers

HIV-1 reverse transcription represents the predominant target for pharmacological inhibition of viral replication, but cell-intrinsic mechanisms that can block HIV-1 reverse transcription in a clinically significant way are poorly defined. We find that effective HIV-1 reverse transcription depends o...

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Autors principals: Leng, Jin, Ho, Hsin-Pin, Buzon, Maria J., Pereyra, Florencia, Walker, Bruce D., Yu, Xu G., Chang, Emmanuel J., Lichterfeld, Mathias
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072498/
https://ncbi.nlm.nih.gov/pubmed/24922574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.05.011
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