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Challenges and developing solutions for increasing the benefits of IL-2 treatment in tumor therapy

Interleukin-2 (IL-2) is a cytokine with pleiotropic effects on the immune system. Systemic IL-2 treatment has produced durable responses in melanoma and renal cancer patients, but unfortunately this is effective only in a fraction of patients. Moreover, IL-2 treatment also engenders serious side eff...

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Detalhes bibliográficos
Main Authors: Skrombolas, Denise, Frelinger, John G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072333/
https://ncbi.nlm.nih.gov/pubmed/24410537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/1744666X.2014.875856
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