Characterization of a Novel Anti-DR5 Monoclonal Antibody WD1 with the Potential to Induce Tumor Cell Apoptosis

TNF-related apoptosis-inducing ligand (TRAIL) is a TNF family member capable of inducing apoptosis. Death receptor 5 (DR 5) is a key receptor of TRAIL and plays an important role in TRAIL-induced apoptosis. To prepare monoclonal antibodies (mAbs) against DR5, cDNA encoding soluble DR5 (sDR5) was fir...

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Bibliografische gegevens
Hoofdauteurs: Wang, Jing, Lin, Zhou, Qiao, Chunxia, Lv, Ming, Yu, Ming, Xiao, He, Wang, Qingyang, Wang, Liyan, Feng, Jiannan, Shen, Beifen, Ma, Yangfang, Li, Yan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072327/
https://ncbi.nlm.nih.gov/pubmed/18318995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2008.7
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