Potent anti-angiogenesis and anti-tumor activity of a novel human anti-VEGF antibody, MIL60

Angiogenesis is crucial for tumor development, growth and metastasis. Vascular endothelial growth factor (VEGF) has been implicated in promoting solid tumor growth and metastasis via stimulating tumor-associated angiogenesis, and blocking the activity of VEGF can starve tumors. Avastin, which is a h...

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Main Authors: Yang, Jing, Wang, Qun, Qiao, Chunxia, Lin, Zhou, Li, Xinying, Huang, Yifei, Zhou, Tingting, Li, Yan, Shen, Beifen, Lv, Ming, Feng, Jiannan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085495/
https://ncbi.nlm.nih.gov/pubmed/24608894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.6
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