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Interferon-γ Promotes Vascular Remodeling in Human Microvascular Endothelial Cells by Upregulating Endothelin (ET)-1 and Transforming Growth Factor (TGF) β2

Systemic sclerosis (SSc) is a complex disease characterized by vascular alterations, activation of the immune system and tissue fibrosis. Previous studies have implicated activation of the interferon pathways in the pathogenesis of SSc. The goal of this study was to determine whether interferon type...

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Detalhes bibliográficos
Main Authors: CHROBAK, IZABELA, LENNA, STEFANIA, STAWSKI, LUKASZ, TROJANOWSKA, MARIA
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072032/
https://ncbi.nlm.nih.gov/pubmed/23359533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24337
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