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Construction of helper plasmid-mediated dual-display phage for autoantibody screening in serum

M13 filamentous bacteriophage has been used in displaying disease-specific antibodies, biomarkers, and peptides. One of the major drawbacks of using phage in diagnostic assays is the aspecific adsorption of proteins leading to a high background signal and decreasing sensitivity. To deal with this, w...

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Autors principals: Rajaram, Kaushik, Vermeeren, Veronique, Somers, Klaartje, Somers, Veerle, Michiels, Luc
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072019/
https://ncbi.nlm.nih.gov/pubmed/24764015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-014-5713-8
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