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Global Fold of Human Cannabinoid Type 2 Receptor Probed by Solid-State (13)C-, (15)N-MAS NMR and Molecular Dynamics Simulations

The global fold of human cannabinoid type 2 (CB(2)) receptor in the agonist-bound active state in lipid bilayers was investigated by solid-state (13)C- and (15)N magic-angle spinning (MAS) NMR, in combination with chemical-shift prediction from a structural model of the receptor obtained by microsec...

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Hlavní autoři: Kimura, Tomohiro, Vukoti, Krishna, Lynch, Diane L., Hurst, Dow P., Grossfield, Alan, Pitman, Michael C., Reggio, Patricia H., Yeliseev, Alexei A., Gawrisch, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071771/
https://ncbi.nlm.nih.gov/pubmed/23999926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24411
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