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Recombinant Cannabinoid Type 2 Receptor in Liposome Model Activates G Protein in Response to Anionic Lipid Constituents

Human cannabinoid type 2 (CB(2)) receptor expressed in Escherichia coli was purified and successfully reconstituted in the functional form into lipid bilayers composed of POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-l-serine (POPS), and cholestery...

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Detalhes bibliográficos
Main Authors: Kimura, Tomohiro, Yeliseev, Alexei A., Vukoti, Krishna, Rhodes, Steven D., Cheng, Kejun, Rice, Kenner C., Gawrisch, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281699/
https://ncbi.nlm.nih.gov/pubmed/22134924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.268425
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