Location, Structure, and Dynamics of the Synthetic Cannabinoid Ligand CP-55,940 in Lipid Bilayers

The widely used hydrophobic cannabinoid ligand CP-55,940 partitions with high efficiency into biomembranes. We studied the location, orientation, and dynamics of CP-55,940 in POPC bilayers by solid-state NMR. Chemical-shift perturbation of POPC protons from the aromatic ring-current effect, as well...

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Hauptverfasser: Kimura, Tomohiro, Cheng, Kejun, Rice, Kenner C., Gawrisch, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2009
Schlagworte:
Membrane
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712040/
https://ncbi.nlm.nih.gov/pubmed/19527650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.033
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