Evaluation of cytochrome P450 2D6 phenotyping in healthy adult Western Indians

BACKGROUND: Cytochrome P450 2D6 (CYP2D6) metabolizes around 25% of the drugs used in therapeutics and different polymorphisms have been identified in various populations. This study aimed at finding the prevalence of CYP2D6 polymorphisms using dextromethorphan as a probe drug. MATERIALS AND METHODS:...

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Autori principali: Gogtay, Nithya J., Mali, Nitin B., Iyer, Krishna, Kadam, Prashant P., Sridharan, Kannan, Shrimal, Divya, Thatte, Urmila M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Medknow Publications & Media Pvt Ltd 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071701/
https://ncbi.nlm.nih.gov/pubmed/24987171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.132154
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