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Protracted withdrawal from cocaine self-administration flips the switch on 5-HT(1B) receptor modulation of cocaine-abuse related behaviors

BACKGROUND: The role of serotonin-1B receptors (5-HT(1B)Rs) in modulating cocaine abuse-related behaviors has been controversial due to discrepancies between pharmacological and gene knockout approaches, and opposite influences on cocaine selfadministration versus cocaine-seeking behavior. We hypoth...

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Autori principali: Pentkowski, Nathan S., Cheung, Tim H.C., Toy, William A., Adams, Matthew D., Neumaier, John F., Neisewander, Janet L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071622/
https://ncbi.nlm.nih.gov/pubmed/22541946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.03.024
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