Stimulation of 5-HT(1B) receptors enhances cocaine reinforcement yet reduces cocaine-seeking behavior

Paradoxically, stimulation of 5-HT(1B) receptors (5-HT(1B)Rs) enhances sensitivity to the reinforcing effects of cocaine but attenuates incentive motivation for cocaine as measured using the extinction/reinstatement model. We revisited this issue by examining the effects of a 5-HT(1B)R agonist, CP94...

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Bibliografiske detaljer
Main Authors: Pentkowski, Nathan S., Acosta, Jazmin I., Browning, Jenny R., Hamilton, Elizabeth C., Neisewander, Janet L.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846432/
https://ncbi.nlm.nih.gov/pubmed/19650818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2009.00162.x
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