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Local Injection of Deferoxamine Improves Neovascularization in Ischemic Diabetic Random Flap by Increasing HIF-1α and VEGF Expression

BACKGROUND: Although the systemic administration of deferoxamine (DFO) is protective in experimental models of normal ischemic flap and diabetic wound, its effect on diabetic flap ischemia using a local injection remains unknown. OBJECTIVE: To explore the feasibility of local injection of DFO to imp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Chen, Cai, Yuanyuan, Zhang, Yun, Xiong, Zhuyou, Li, Guangzao, Cui, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071063/
https://ncbi.nlm.nih.gov/pubmed/24963878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100818
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