The peroxisome proliferator–activated receptor β/δ agonist GW0742 has direct protective effects on right heart hypertrophy

Abstract. Pulmonary hypertension is a debilitating disease with no cure. We have previously shown that peroxisome proliferator–activated receptor (PPAR) β/δ agonists protect the right heart in hypoxia-driven pulmonary hypertension without affecting vascular remodeling. PPARβ/δ is an important recept...

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Hlavní autoři: Kojonazarov, Baktybek, Luitel, Himal, Sydykov, Akylbek, Dahal, Bhola K., Paul-Clark, Mark J., Bonvini, Sara, Reed, Anna, Schermuly, Ralph T., Mitchell, Jane A.
Médium: Artigo
Jazyk:Inglês
Vydáno: University of Chicago Press 2013
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070821/
https://ncbi.nlm.nih.gov/pubmed/25006409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/674755
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