Llwytho...

Subcellular mechanisms in pulmonary arterial hypertension: combinatorial modalities that inhibit anterograde trafficking and cause bone morphogenetic protein receptor type 2 mislocalization

Abstract. The natural history of familial pulmonary arterial hypertension (PAH) typically involves mutations in and/or haploinsuffciency of BMPR2 (gene for bone morphogenetic protein receptor type 2) but with low penetrance (10%–15%), delayed onset (in the third or fourth decade), and a gender bias...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Yang-Ming, Lane, Kirk B., Sehgal, Pravin B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: University of Chicago Press 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070808/
https://ncbi.nlm.nih.gov/pubmed/24618539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/674336
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