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Reactive oxygen species scavengers improve voltage-gated K(+) channel function in pulmonary arteries of newborn pigs with progressive hypoxia-induced pulmonary hypertension

Abstract. Changes in voltage-gated K(+) (Kv) channel function contribute to the pathogenesis of pulmonary hypertension. Yet the mechanisms underlying Kv channel impairments in the pulmonary circulation remain unclear. We tested the hypothesis that reactive oxygen species (ROSs) contribute to the Kv...

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Detaylı Bibliyografya
Asıl Yazarlar: Fike, Candice D., Aschner, Judy L., Kaplowitz, Mark R., Zhang, Yongmei, Madden, Jane A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: University of Chicago Press 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070796/
https://ncbi.nlm.nih.gov/pubmed/24618540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/674307
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