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Reactive oxygen species scavengers improve voltage-gated K(+) channel function in pulmonary arteries of newborn pigs with progressive hypoxia-induced pulmonary hypertension

Abstract. Changes in voltage-gated K(+) (Kv) channel function contribute to the pathogenesis of pulmonary hypertension. Yet the mechanisms underlying Kv channel impairments in the pulmonary circulation remain unclear. We tested the hypothesis that reactive oxygen species (ROSs) contribute to the Kv...

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Detalhes bibliográficos
Main Authors: Fike, Candice D., Aschner, Judy L., Kaplowitz, Mark R., Zhang, Yongmei, Madden, Jane A.
Formato: Artigo
Idioma:Inglês
Publicado em: University of Chicago Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070796/
https://ncbi.nlm.nih.gov/pubmed/24618540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/674307
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