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Regulation of APC/C Activators in Mitosis and Meiosis

The anaphase-promoting complex/cyclosome is a multi-subunit E3 ubiquitin ligase that triggers the degradation of multiple substrates during mitosis. Cdc20/Fizzy and Cdh1/Fizzy-related activate the APC/C and confer substrate specificity through complex interactions with both the core APC/C and substr...

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Detalhes bibliográficos
Main Authors: Pesin, Jillian A., Orr-Weaver, Terry L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070676/
https://ncbi.nlm.nih.gov/pubmed/18598214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.cellbio.041408.115949
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