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Spindle checkpoint activation at meiosis I advances anaphase II onset via meiosis-specific APC/C regulation
During mitosis, the spindle assembly checkpoint (SAC) inhibits the Cdc20-activated anaphase-promoting complex/cyclosome (APC/C(Cdc20)), which promotes protein degradation, and delays anaphase onset to ensure accurate chromosome segregation. However, the SAC function in meiotic anaphase regulation is...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483520/ https://ncbi.nlm.nih.gov/pubmed/18644893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200802053 |
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