ELK1 transcription factor linked to dysregulated striatal mu opioid receptor signaling network and OPRM1 polymorphism in human heroin abusers

BACKGROUND: Abuse of heroin and prescription opiate medications has grown to disturbing levels. Opioids mediate their effects through mu opioid receptors (MOR), but minimal information exists regarding MOR-related striatal signaling relevant to the human condition. The striatum is a structure centra...

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Autors principals: Sillivan, Stephanie E., Whittard, John D., Jacobs, Michelle M., Ren, Yanhua, Mazloom, Amin R., Caputi, Francesca F., Horvath, Monika, Keller, Eva, Ma’ayan, Avi, Pan, Ying-Xian, Chiang, Lillian W., Hurd, Yasmin L.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070524/
https://ncbi.nlm.nih.gov/pubmed/23702428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.04.012
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