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Genome-wide Analysis Reveals Novel and Discrete Functions for Tubulin Carboxy-terminal Tails

BACKGROUND: Microtubules (MTs) support diverse transport and force generation processes in cells. Both α- and β-tubulin proteins possess carboxy-terminal tail regions (CTTs) that are negatively charged, intrinsically disordered, and project from the MT surface where they interact with motors and oth...

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Bibliographic Details
Main Authors: Aiken, Jayne, Sept, David, Costanzo, Michael, Boone, Charles, Cooper, John A., Moore, Jeffrey K.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070440/
https://ncbi.nlm.nih.gov/pubmed/24835459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.03.078
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