Heterogeneity among RIP‐Tag2 insulinomas allows vascular endothelial growth factor‐A independent tumor expansion as revealed by studies in Shb mutant mice: Implications for tumor angiogenesis

The Shb adapter protein is a signaling intermediate that operates downstream of vascular endothelial growth factor receptor‐2 (VEGFR‐2) in endothelial cells. The Shb knockout mouse displays a dysfunctional microvasculature and impaired growth of subcutaneously implanted tumor cells. We decided to in...

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Detalhes bibliográficos
Main Authors: Åkerblom, Björn, Zang, Guangxiang, Zhuang, Zhen W., Calounova, Gabriela, Simons, Michael, Welsh, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070317/
https://ncbi.nlm.nih.gov/pubmed/22336752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.01.006
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