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Heterogeneity among RIP‐Tag2 insulinomas allows vascular endothelial growth factor‐A independent tumor expansion as revealed by studies in Shb mutant mice: Implications for tumor angiogenesis
The Shb adapter protein is a signaling intermediate that operates downstream of vascular endothelial growth factor receptor‐2 (VEGFR‐2) in endothelial cells. The Shb knockout mouse displays a dysfunctional microvasculature and impaired growth of subcutaneously implanted tumor cells. We decided to in...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070317/ https://ncbi.nlm.nih.gov/pubmed/22336752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.01.006 |
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