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A Sequential Bioequivalence Design with a Potential Ethical Advantage
This paper introduces a two-stage approach for evaluation of bioequivalence, where, in contrast to the designs of Diane Potvin and co-workers, two stages are mandatory regardless of the data obtained at stage 1. The approach is derived from Potvin’s method C. It is shown that under circumstances wit...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070248/ https://ncbi.nlm.nih.gov/pubmed/24871343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9622-7 |
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