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Sequential Bioequivalence Trial Designs with Increased Power and Controlled Type I Error Rates
Methods to implement two-stage designs in two-treatment, two-sequence, and two-period crossover bioequivalence studies have only recently been developed. The two-stage methods have so far only been described for a targeted study power of 80%. Since it is sometimes desirable to increase the targeted...
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| Natura: | Artigo |
| Lingua: | Inglês |
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Springer US
2013
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3691437/ https://ncbi.nlm.nih.gov/pubmed/23543603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9475-5 |
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