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Inhibition of ATM kinase activity enhanced TRAIL-mediated apoptosis in human melanoma cells
The aim of the present study was to elucidate the effects of ATM kinase on the regulation of the extrinsic TRAIL-R2/DR5-mediated death pathway in human melanoma cells. We revealed that total ATM protein levels were high in some human melanoma lines compared to normal cells. The basal levels of activ...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070218/ https://ncbi.nlm.nih.gov/pubmed/19351839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3883 |
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