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Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression
Although many human melanomas express the death receptors TRAIL-R2/DR5 or TRAIL-R1/DR4 on cell surface, they often exhibit resistance to exogenous TRAIL. One of the main contributors to TRAIL-resistance of melanoma cells is upregulation of transcription factors STAT3 and NF-κB that control the expre...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738302/ https://ncbi.nlm.nih.gov/pubmed/18222423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.12.012 |
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