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Paradoxical Results in Perturbation-Based Signaling Network Reconstruction

Mathematical models are extensively employed to understand physicochemical processes in biological systems. In the absence of detailed mechanistic knowledge, models are often based on network inference methods, which in turn rely upon perturbations to nodes by biochemical means. We have discovered a...

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Detalles Bibliográficos
Main Authors: Prabakaran, Sudhakaran, Gunawardena, Jeremy, Sontag, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070074/
https://ncbi.nlm.nih.gov/pubmed/24940789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.031
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