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Leptin deficiency recapitulates the histological features of pulmonary arterial hypertension in mice

Leptin is a neuroendocrine peptide released by adipose tissue that enhances metabolism and acts on the hypothalamus to suppress appetite. Leptin also regulates aspects of cardiovascular function and low serum leptin has been associated with increased mortality in humans. We hypothesized that leptin...

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Autori principali: Aytekin, Metin, Tonelli, Adriano R, Farver, Carol F, Feldstein, Ariel E, Dweik, Raed A
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069962/
https://ncbi.nlm.nih.gov/pubmed/24966903
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