Interleukin-18 as a Therapeutic Target in Acute Myocardial Infarction and Heart Failure

Interleukin 18 (IL-18) is a proinflammatory cytokine in the IL-1 family that has been implicated in a number of disease states. In animal models of acute myocardial infarction (AMI), pressure overload, and LPS-induced dysfunction, IL-18 regulates cardiomyocyte hypertrophy and induces cardiac contrac...

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Main Authors: O’Brien, Laura C, Mezzaroma, Eleonora, Van Tassell, Benjamin W, Marchetti, Carlo, Carbone, Salvatore, Abbate, Antonio, Toldo, Stefano
Formato: Artigo
Idioma:Inglês
Publicado: ScholarOne 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069269/
https://ncbi.nlm.nih.gov/pubmed/24804827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00034
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