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Quantitative evaluation of boron neutron capture therapy (BNCT) drugs for boron delivery and retention at subcellular scale resolution in human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS)

Boron neutron capture therapy (BNCT) of cancer depends on the selective delivery of a sufficient number of boron-10 ((10)B) atoms to individual tumor cells. Cell killing results from the (10)B (n, α)(7)Li neutron capture and fission reactions that occur if a sufficient number of (10)B atoms are loca...

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Detalhes bibliográficos
Main Authors: Chandra, S., Ahmad, T., Barth, R. F., Kabalka, G. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069218/
https://ncbi.nlm.nih.gov/pubmed/24684609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jmi.12126
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