Dipeptidyl Peptidase IV Inhibitor MK-0626 Attenuates Pancreatic Islet Injury in Tacrolimus-Induced Diabetic Rats

BACKGROUND: Tacrolimus (TAC)-induced pancreatic islet injury is one of the important causes of new-onset diabetes in transplant recipients. This study was performed to evaluate whether a dipeptidyl peptidase IV (DPP IV) inhibitor is effective in improving TAC-induced diabetes mellitus by reducing pa...

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Main Authors: Jin, Long, Lim, Sun Woo, Doh, Kyoung Chan, Piao, Shang Guo, Jin, Jian, Heo, Seong Beom, Chung, Byung Ha, Yang, Chul Woo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069160/
https://ncbi.nlm.nih.gov/pubmed/24959755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100798
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