Chimeric Avidin – NMR Structure and Dynamics of a 56 kDa Homotetrameric Thermostable Protein

Chimeric avidin (ChiAVD) is a product of rational protein engineering remarkably resistant to heat and harsh conditions. In quest of the fundamentals behind factors affecting stability we have elucidated the solution NMR spectroscopic structure of the biotin–bound form of ChiAVD and characterized th...

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Autors principals: Tossavainen, Helena, Kukkurainen, Sampo, Määttä, Juha A. E., Kähkönen, Niklas, Pihlajamaa, Tero, Hytönen, Vesa P., Kulomaa, Markku S., Permi, Perttu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069078/
https://ncbi.nlm.nih.gov/pubmed/24959850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100564
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