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Chimeric Avidin – NMR Structure and Dynamics of a 56 kDa Homotetrameric Thermostable Protein

Chimeric avidin (ChiAVD) is a product of rational protein engineering remarkably resistant to heat and harsh conditions. In quest of the fundamentals behind factors affecting stability we have elucidated the solution NMR spectroscopic structure of the biotin–bound form of ChiAVD and characterized th...

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Detalhes bibliográficos
Main Authors: Tossavainen, Helena, Kukkurainen, Sampo, Määttä, Juha A. E., Kähkönen, Niklas, Pihlajamaa, Tero, Hytönen, Vesa P., Kulomaa, Markku S., Permi, Perttu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069078/
https://ncbi.nlm.nih.gov/pubmed/24959850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100564
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