Long-Term Treatment with the Sodium Glucose Cotransporter 2 Inhibitor, Dapagliflozin, Ameliorates Glucose Homeostasis and Diabetic Nephropathy in db/db Mice

Inhibition of sodium glucose cotransporter 2 (SGLT2) has been reported as a new therapeutic strategy for treating diabetes. However, the effect of SGLT2 inhibitors on the kidney is unknown. In addition, whether SGLT2 inhibitors have an anti-inflammatory or antioxidative stress effect is still unclea...

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Detalhes bibliográficos
Main Authors: Terami, Naoto, Ogawa, Daisuke, Tachibana, Hiromi, Hatanaka, Takashi, Wada, Jun, Nakatsuka, Atsuko, Eguchi, Jun, Horiguchi, Chikage Sato, Nishii, Naoko, Yamada, Hiroshi, Takei, Kohji, Makino, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069074/
https://ncbi.nlm.nih.gov/pubmed/24960177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100777
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