Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer’s disease: a 6-month, randomized, placebo-controlled, multicenter trial

PURPOSE: A link between poor sleep quality and Alzheimer’s disease (AD) has recently been suggested. Since endogenous melatonin levels are already reduced at preclinical AD stages, it is important to ask whether replenishing the missing hormone would be beneficial in AD and whether any such effects...

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Bibliografiske detaljer
Main Authors: Wade, Alan G, Farmer, Mildred, Harari, Gil, Fund, Naama, Laudon, Moshe, Nir, Tali, Frydman-Marom, Anat, Zisapel, Nava
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069047/
https://ncbi.nlm.nih.gov/pubmed/24971004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S65625
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