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Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer’s disease: a 6-month, randomized, placebo-controlled, multicenter trial

PURPOSE: A link between poor sleep quality and Alzheimer’s disease (AD) has recently been suggested. Since endogenous melatonin levels are already reduced at preclinical AD stages, it is important to ask whether replenishing the missing hormone would be beneficial in AD and whether any such effects...

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Main Authors: Wade, Alan G, Farmer, Mildred, Harari, Gil, Fund, Naama, Laudon, Moshe, Nir, Tali, Frydman-Marom, Anat, Zisapel, Nava
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069047/
https://ncbi.nlm.nih.gov/pubmed/24971004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S65625
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