Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer’s disease: a 6-month, randomized, placebo-controlled, multicenter trial

PURPOSE: A link between poor sleep quality and Alzheimer’s disease (AD) has recently been suggested. Since endogenous melatonin levels are already reduced at preclinical AD stages, it is important to ask whether replenishing the missing hormone would be beneficial in AD and whether any such effects...

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Detalhes bibliográficos
Main Authors: Wade, Alan G, Farmer, Mildred, Harari, Gil, Fund, Naama, Laudon, Moshe, Nir, Tali, Frydman-Marom, Anat, Zisapel, Nava
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069047/
https://ncbi.nlm.nih.gov/pubmed/24971004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S65625
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