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Impaired Emotional Learning and Involvement of the Corticotropin-Releasing Factor Signaling System in Patients with Irritable Bowel Syndrome
BACKGROUND & AIMS: Alterations in central corticotropin-releasing factor (CRF) signaling pathways have been implicated in the pathophysiology of anxiety disorders and irritable bowel syndrome (IBS). We aimed to characterize the effects of the CRF receptor 1 (CRF-R1) antagonist, GW876008, on brai...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4069031/ https://ncbi.nlm.nih.gov/pubmed/23954313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.08.016 |
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