Thrombin Increases Lung Fibroblast Survival while Promoting Alveolar Epithelial Cell Apoptosis via the Endoplasmic Reticulum Stress Marker, CCAAT Enhancer–Binding Homologous Protein

Apoptosis of alveolar epithelial cells (AECs) and survival of lung fibroblasts are critical events in the pathogenesis of pulmonary fibrosis; however, mechanisms underlying the apoptosis of AECs and the resistance of lung fibroblasts to apoptosis remain obscure. Herein, we demonstrate that the fate...

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Bibliographische Detailangaben
Hauptverfasser: Atanelishvili, Ilia, Liang, Jun, Akter, Tanjina, Spyropoulos, Demetri D., Silver, Richard M., Bogatkevich, Galina S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2014
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068946/
https://ncbi.nlm.nih.gov/pubmed/24279877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0317OC
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