Gata5 Deficiency Causes Airway Constrictor Hyperresponsiveness in Mice

Gata5 is a transcription factor expressed in the lung, but its physiological role is unknown. To test whether and how Gata5 regulates airway constrictor responsiveness, we studied Gata5(−/−), Gata5(+/−), and wild-type mice on the C57BL/6J background. Cholinergic airway constrictor responsiveness was...

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Détails bibliographiques
Auteurs principaux: Chen, Bohao, Moore, Tamson V., Li, Zhenping, Sperling, Anne I., Zhang, Chunling, Andrade, Jorge, Rodriguez, Alex, Bahroos, Neil, Huang, Yong, Morrisey, Edward E., Gruber, Peter J., Solway, Julian
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2014
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068924/
https://ncbi.nlm.nih.gov/pubmed/24199649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0294OC
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