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Upstream stimulatory factor 1 activates GATA5 expression through an E-box motif

Silencing of GATA5 gene expression as a result of promoter hypermethylation has been observed in lung, gastrointestinal, and ovarian cancers. However, the regulation of GATA5 gene expression has been poorly understood. Here, we demonstrate that an enhancer (E)-box in the GATA5 promoter (bp −118 to −...

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Autors principals: Chen, Bohao, Hsu, Rona, Li, Zhenping, Kogut, Paul C., Du, Qingxia, Rouser, Kelly, Camoretti-Mercado, Blanca, Solway, Julian
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677829/
https://ncbi.nlm.nih.gov/pubmed/22625849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111942
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