Inhibition of Transglutaminase 2, a Novel Target for Pulmonary Fibrosis, by Two Small Electrophilic Molecules

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive fibrotic destruction of normal lung architecture. Due to a lack of effective treatment options, new treatment approaches are needed. We previously identified transglutaminase (TG)2, a multifunctional protein expressed by human lung...

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Bibliographische Detailangaben
Hauptverfasser: Olsen, Keith C., Epa, Amali P., Kulkarni, Ajit A., Kottmann, R. Matthew, McCarthy, Claire E., Johnson, Gail V., Thatcher, Thomas H., Phipps, Richard P., Sime, Patricia J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068920/
https://ncbi.nlm.nih.gov/pubmed/24175906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0092OC
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