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Uptake of Polymyxin B into Renal Cells
Polymyxin B is increasingly used as a treatment of last resort against multidrug-resistant Gram-negative infections. Using a mammalian kidney cell line, we demonstrated that polymyxin B uptake into proximal tubular epithelial cells was saturable and occurred primarily through the apical membrane, su...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068554/ https://ncbi.nlm.nih.gov/pubmed/24733472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02557-14 |
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