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Uptake of Polymyxin B into Renal Cells

Polymyxin B is increasingly used as a treatment of last resort against multidrug-resistant Gram-negative infections. Using a mammalian kidney cell line, we demonstrated that polymyxin B uptake into proximal tubular epithelial cells was saturable and occurred primarily through the apical membrane, su...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Abdelraouf, Kamilia, Chang, Kai-Tai, Yin, Taijun, Hu, Ming, Tam, Vincent H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068554/
https://ncbi.nlm.nih.gov/pubmed/24733472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02557-14
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