Characterization of a Respiratory Syncytial Virus L Protein Inhibitor

The respiratory syncytial virus (RSV) L protein is a viral RNA-dependent RNA polymerase that contains multiple enzyme activities required for RSV replication. The RSV L inhibitors described in literature are limited by their cytotoxicity or the lack of RSV B subtype coverage. Here, we characterize a...

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Bibliografiske detaljer
Main Authors: Tiong-Yip, Choi-Lai, Aschenbrenner, Lisa, Johnson, Kenneth D., McLaughlin, Robert E., Fan, Jun, Challa, SreeRupa, Xiong, Hui, Yu, Qin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068518/
https://ncbi.nlm.nih.gov/pubmed/24777090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02540-14
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