High Proportion of Heteroresistance in gyrA and gyrB in Fluoroquinolone-Resistant Mycobacterium tuberculosis Clinical Isolates

Heteroresistance is the coexistence of populations with differing nucleotides at a drug resistance locus within a sample of organisms. Although Sanger sequencing is the gold standard for sequencing, it may be less sensitive than deep sequencing for detecting fluoroquinolone heteroresistance in Mycob...

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Autori principali: Eilertson, Brandon, Maruri, Fernanda, Blackman, Amondrea, Herrera, Miguel, Samuels, David C., Sterling, Timothy R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068501/
https://ncbi.nlm.nih.gov/pubmed/24687490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02066-13
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