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Pharmacokinetics of Cefuroxime in Porcine Cortical and Cancellous Bone Determined by Microdialysis

Traditionally, the pharmacokinetics of antimicrobials in bone have been investigated using bone biopsy specimens, but this approach suffers from considerable methodological limitations. Consequently, new methods are needed. The objectives of this study were to assess the feasibility of microdialysis...

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Detalhes bibliográficos
Main Authors: Tøttrup, Mikkel, Hardlei, Tore Forsingdal, Bendtsen, Michael, Bue, Mats, Brock, Birgitte, Fuursted, Kurt, Søballe, Kjeld, Birke-Sørensen, Hanne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068497/
https://ncbi.nlm.nih.gov/pubmed/24663019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02438-14
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