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Pharmacokinetics of Cefuroxime in Porcine Cortical and Cancellous Bone Determined by Microdialysis

Traditionally, the pharmacokinetics of antimicrobials in bone have been investigated using bone biopsy specimens, but this approach suffers from considerable methodological limitations. Consequently, new methods are needed. The objectives of this study were to assess the feasibility of microdialysis...

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Autores principales: Tøttrup, Mikkel, Hardlei, Tore Forsingdal, Bendtsen, Michael, Bue, Mats, Brock, Birgitte, Fuursted, Kurt, Søballe, Kjeld, Birke-Sørensen, Hanne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068497/
https://ncbi.nlm.nih.gov/pubmed/24663019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02438-14
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