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Pharmacokinetics of Cefuroxime in Porcine Cortical and Cancellous Bone Determined by Microdialysis

Traditionally, the pharmacokinetics of antimicrobials in bone have been investigated using bone biopsy specimens, but this approach suffers from considerable methodological limitations. Consequently, new methods are needed. The objectives of this study were to assess the feasibility of microdialysis...

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Bibliografiske detaljer
Main Authors: Tøttrup, Mikkel, Hardlei, Tore Forsingdal, Bendtsen, Michael, Bue, Mats, Brock, Birgitte, Fuursted, Kurt, Søballe, Kjeld, Birke-Sørensen, Hanne
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068497/
https://ncbi.nlm.nih.gov/pubmed/24663019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02438-14
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