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Sulfur Mobilization for Fe-S Cluster Assembly by the Essential SUF Pathway in the Plasmodium falciparum Apicoplast and Its Inhibition

The plastid of the malaria parasite, the apicoplast, is essential for parasite survival. It houses several pathways of bacterial origin that are considered attractive sites for drug intervention. Among these is the sulfur mobilization (SUF) pathway of Fe-S cluster biogenesis. Although the SUF pathwa...

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Detalhes bibliográficos
Main Authors: Charan, Manish, Singh, Nidhi, Kumar, Bijay, Srivastava, Kumkum, Siddiqi, Mohammad Imran, Habib, Saman
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068488/
https://ncbi.nlm.nih.gov/pubmed/24709262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02711-13
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